Author(s)
Yunpeng Wang
Published 23 Projects
First Episode Genetics Diffusivity Sleep Polygenic Risk Score
Content
Video Abstract (AI generated) (01:14) Paper Preprint (github,"")Summary: Post-GWAS studies using the results from large consortium meta-analysis often need to correctly take care of the overlapping sample issue. The gold standard approach for resolving this issue is to reperform the GWAS or meta-analysis excluding the overlapped participants. However, such approach is time-consuming and, sometimes, restricted by the available data. deMeta provides a user friendly and computationally efficient command-line implementation for removing the effect of a contributing sub-study to a consortium from the meta-analysis results. Only the summary statistics of the meta-analysis the sub-study to be removed are required. In addition, deMeta can generate contrasting Manhattan and quantile-quantile plots for users to visualize the impact of the sub-study on the meta-analysis results. Availability and Implementation: The python source code, examples and documentations of deMeta are publicly available at https://github.com/Computational-NeuroGenetics/deMeta-beta . ### Competing Interest Statement The authors have declared no competing interest.
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Yunpeng Wang. (2021, Oct 28).deMeta: Removing sub-studies from meta-analysis of genome wide association studies (GWAS)[Video]. Scitok. https://scitok.com/project/p/a6dcb05f
Sun Jiangming. "deMeta: Removing sub-studies from meta-analysis of genome wide association studies (GWAS)" Scitok, uploaded by Wang Yunpeng, 28 Oct, 2021, https://scitok.com/project/pa6dcb05f
Yunpeng Wang. "deMeta: Removing sub-studies from meta-analysis of genome wide association studies (GWAS)" Scitok. (Oct 28, 2021). https://scitok.com/project/p/a6dcb05f
Yunpeng Wang (Oct 28, 2021). deMeta: Removing sub-studies from meta-analysis of genome wide association studies (GWAS) Scitok. https://scitok.com/project/p/a6dcb05f
Yunpeng Wang. deMeta: Removing sub-studies from meta-analysis of genome wide association studies (GWAS)[video]. 2021 Oct 28. https://scitok.com/project/p/a6dcb05f
@online{al2006link, title={ deMeta: Removing sub-studies from meta-analysis of genome wide association studies (GWAS) }, author={ Wang, Yunpeng }, organization={Scitok}, month={ Oct }, day={ 28 }, year={ 2021 }, url = {https://scitok.com/project/p/a6dcb05f}, }